Subject(s)
Humans , Family Planning Services , Pandemics , Contraception , Contraceptive Agents , CounselingABSTRACT
Since the outbreak of severe acute respiratory coronavirus 2 (SARS-CoV-2), the coronavirus disease 2019 has had a wide range of effects on human health. This paper summarizes the data related to the effects of the SARS-CoV-2 infection on human reproduction. Both the male and female reproductive tract express high levels of receptors and proteins needed for viral cell entry. There is presently no evidence that gametes are affected by the infection. Male fertility may be temporarily reduced due to inflammatory responses following infection. The endometrium is highly susceptible to SARS-CoV-2 cell entry; however, it remains unclear whether this could alter receptivity and embryo implantation. Menstrual cycle changes were reported in women who experienced severe infection; however, they tended to be reversible. For couples undergoing assisted reproduction treatment, the pandemic led to a significant psychological burden, with changes in lifestyle that could directly affect the success of the treatment. Human reproduction societies recommend screening all patients prior to cycle initiation and avoiding treatment of women with severe comorbidities until the pandemic is under control. Finally, for pregnant women, it is expected that the infection is more severe in women in the third trimester and in those with comorbidities. Those who are symptomatic for SARS-CoV-2 are more likely to have increased rates of prematurity and intrapartum fetal distress than those who are asymptomatic. Vertical transmission cannot be completely ruled out, but neonatal infection rates are low. Vaccination appears to be safe and is indicated for use in pregnant and lactating women because the benefits outweigh the risks.
Subject(s)
Humans , Male , Female , Pregnancy , Pregnancy Complications, Infectious/epidemiology , COVID-19 , Reproduction , Lactation , SARS-CoV-2ABSTRACT
INTRODUCTION: Abortion, even when provided by law in cases of sexual violence, continues to be practiced in an insecure way, since women who suffer violence are not reported or guarded by social, institutional or age vulnerability, as in adolescence. OBJECTIVE: Describe the clinical consequences of unsafe abortion, report this experience as well as sexual violence in situations of social and age vulnerability. METHODS: It is a clinical case report, with the consent of the patient, in the year 2016, of a 16-year-old female adolescent with a personal history of sexual violence by an intimate aggressor. Admitted to the health service with diagnosis of acute abdomen and induced abortion using antibiotic therapy. RESULTS: Laboratory tests revealed altered C reactive protein and presence of leukocytosis, ultrasound showed heterogenic mass, computed tomography showed presence of cylindrical foreign body in vaginal cavity, surgical interventions, sepsis, clinical complications (pulmonary thromboembolism) and prolonged hospitalization. CONCLUSION: The history of violence portrayed in this study reveals an attempt of abortion with self harm, revealing negative clinical repercussions and the health problems of the adolescent. This person has committed an abortion that does not fit into the abortion criteria provided by law. It also revealed the need for further discussion on the topic, highlighting health promotion practices against unsafe abortion.
INTRODUÇÃO: O aborto, mesmo quando previsto por lei nos casos de violência sexual, continua a ser praticado de maneira insegura, uma vez que as mulheres que experimentam essa violência não a relatam ou velam por vulnerabilidade social, institucional ou etária, como na adolescência. OBJETIVO: Descrever as consequências clínicas do aborto inseguro e relatar essa experiência vivenciada bem como a violência sexual em situações de vulnerabilidade social e etária MÉTODO: Trata se de relato de caso clínico, com consentimento da paciente, ocorrido no ano de 2016 de uma adolescente, sexo feminino, 16 anos com antecedente pessoal de violência sexual de agressor íntimo. Admitida em serviço de saúde com diagnóstico de abdome agudo e aborto induzido em uso de antibioticoterapia. RESULTADOS: Laboratoriais revelaram proteína C reativa alterada e presença de leucocitose, ultrassonografia apresentou massa heterogênica, tomográfica computadorizada evidenciou presença de corpo estranho cilíndrico em cavidade vaginal, intervenções cirúrgicas, infecções generalizadas, complicações clínicas. CONCLUSÃO: A história de violência retratada nesse estudo revela uma tentativa de aborto com autolesão, desvelando repercussões clínicas negativas e os agravos à saúde da adolescente. Esta que cometeu um aborto que não se insere nos critérios de aborto previsto por lei. Revelou ainda a necessidade de maior discussão sobre o tema, destacando as práticas de promoção da saúde contra o aborto inseguro.
Subject(s)
Humans , Male , Female , Pregnancy , Adolescent , Sex Offenses , Adolescent , Abortion, Septic , AbortionABSTRACT
Objetivo Investigar os efeitos do tratamento oncológico no sistema auditivo de crianças. Métodos A amostra foi constituída por 12 crianças de 2 a 12 anos de idade, com diagnóstico de câncer e indicação para radioterapia associada ou não à quimioterapia. Foram realizadas pesquisas das emissões otoacústicas produto de distorção (EOA-PD) e emissões otoacústicas transientes (EOA-TE), antes e após seis meses de tratamento. Resultados Das 24 orelhas, apenas duas (8,3%) falharam para as EOA-TE e EOA-PD e não foi observada alteração significativa após o tratamento oncológico. Conclusão O tratamento oncológico, durante um período de seis meses, não ocasionou alterações auditivas nesta amostra. .
Purpose To investigate the effects of cancer treatment on the auditory system of children. Methods The study population comprised 12 children, aged 2 to 12 years, who had been diagnosed with cancer and recommended radiotherapy with/without chemotherapy. Distortion product otoacoustic emissions (DP-OAE) and transient evoked otoacoustic emissions OAE (TE-OAE) were measured before treatment and after six months of treatment. Results Out of the 24 ears, only two ears (8.3%) failed the TE-OAE and DP-OAE tests, and no significant change was observed after cancer treatment. Conclusion Cancer treatment over a period of six months did not cause hearing impairment in this group of patients. .
Subject(s)
Humans , Child, Preschool , Child , Drug-Related Side Effects and Adverse Reactions , Hearing Loss , Neoplasms/drug therapy , Otoacoustic Emissions, Spontaneous , Auditory Threshold/drug effects , Cochlear Duct/drug effects , Drug Therapy , Radiotherapy/adverse effects , ToxicityABSTRACT
Neste manuscrito relatamos o caso de um paciente do sexo masculino, 8 anos de idade, com febre e dificuldade à deambulação, diagnosticado com abscesso de iliopsoas, cujo tratamento com oxacilina foi complicado pelo aparecimento da síndrome DRESS. Ambos são doenças raras, em especial na faixa etária pediátrica, e potencialmente graves...
Subject(s)
Humans , Male , Child , Psoas AbscessABSTRACT
Patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) often have associated changes in craniofacial morphology and distribution of body fat, either alone or in combination. AIM: To correlate cephalometric and anthropometric measures with OSAHS severity by using the apnea-hypopnea index (AHI). METHOD: A retrospective cephalometry study of 93 patients with OSAHS was conducted from July 2010 to July 2012. The following measurements were evaluated: body mass index (BMI), neck circumference (NC), waist circumference (WC), hip circumference (HC), the angles formed by the cranial base and the maxilla (SNA) and the mandible (SNB), the difference between SNA and SNB (ANB), the distance from the mandibular plane to the hyoid bone (MP-H), the space between the base of the tongue and the posterior pharyngeal wall (PAS), and the distance between the posterior nasal spine and the tip of the uvula (PNS-P). Means, standard deviations, and Pearson's correlation coefficients were calculated and analyzed. RESULTS: AHI correlated significantly with BMI (r = 0.207, p = 0.047), NC (r = 0.365, p = 0.000), WC (r = 0.337, p = 0.001), PNS-P (r = 0.282, p = 0.006), and MP-H (r = 0.235, p = 0.023). CONCLUSION: Anthropometric measurements (BMI, NC, and WC) and cephalometric measurements (MP-H and PNS-P) can be used as predictors of OSAHS severity...
Subject(s)
Male , Female , Young Adult , Middle Aged , Aged, 80 and over , Anthropometry , Body Mass Index , Cephalometry , Sleep Apnea, Obstructive , Abdominal Circumference , Waist CircumferenceABSTRACT
Administration of ethanol extract of stem bark from Z. rhoifolium (EEtOH-ZR) induced hypotension associated with a dual effect in heart rate in normotensive rats. This response was highlighted in spontaneously hypertensive rats (SHR). In rat superior mesenteric artery rings, the cumulative addition of EEtOH-ZR (0.1–750 µg/mL) on a phenylephrine-induced pre-contraction (10-5 M) promoted a vasorelaxant effect by a concentration-dependent manner and independent of vascular endothelium. A similar effect was obtained on KCl-induced pre-contractions (80 mM). EEtOH-ZR attenuated contractions induced by cumulative addition of CaCl2 (10-6–3 × 10-2 M) in depolarizing medium without Ca2+ only at 500 or 750 µg/mL. Likewise, on S-(–)-Bay K 8644-induced pre-contractions (10-7 M), the EEtOH-ZR-induced vasorelaxant effect was attenuated. EEtOH-ZR (27, 81, 243 or 500 µg/mL) inhibited contractions induced by cumulative addition of phenylephrine (10-9 - 10-5 M) in endothelium-denuded preparations or by a single concentration (10-5 M) in a Ca2+-free medium. The involvement of K+ channels was evaluated by tetraethylammonium (3 mM); the EEtOH-ZR-induced vasorelaxation was not attenuated. Thus, calcium influx blockade through voltage-operated calcium channels (CaVL) and inhibition of calcium release from intracellular stores are probably underlying EEtOH-ZR-induced cardiovascular effects.
Subject(s)
3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester/pharmacology , Animals , Antihypertensive Agents/pharmacology , Blood Pressure/drug effects , Calcium Channel Agonists/pharmacology , Calcium Channels/drug effects , Calcium Chloride/pharmacology , Endothelium, Vascular/drug effects , Ethanol/chemistry , Male , Phenylephrine/pharmacology , Plant Bark/chemistry , Plant Stems/chemistry , Potassium Channels/drug effects , Potassium Chloride/pharmacology , Rats , Rats, Inbred SHR , Rats, Wistar , Vasoconstrictor Agents/pharmacology , Vasodilation/drug effects , Vasodilator Agents/pharmacology , Zanthoxylum/chemistryABSTRACT
A doença de Kikuchi-Fujimoto é uma linfadenite necrosante rara de bom prognóstico, cujo diagnóstico diferencial inclui principalmente as neoplasias linfoides. Relata-se um caso peculiar de doença de Kikuchi-Fujimoto em paciente jovem, do sexo masculino, com acometimento inguinal bilateral e diagnóstico histopatológico.
The Kikuchi-Fujimoto disease is a rare necrotizing lymphadenitis of good prognosis, differential diagnosis includes mainly lymphoid neoplasms. We report a peculiar case of Kikuchi-Fujimoto disease in a young patient, male, with bilateral inguinal involvement and histopathological diagnosis
ABSTRACT
A cisticercose é uma doença causada pelo parasitismo da larva da tênia do porco (Cysticercus cellulosae) em tecidos humanos. É mais comum no cérebro, tecido subcutâneo, músculos e olhos. Relatamos aqui uma apresentação rara desta doença na margem lateral esquerda da língua, com diagnóstico histopatológico em biópsia excisional e retirada total da lesão. A criança acometida tinha 7 anos de idade, era do sexo masculino e previamente hígida...
Tongue cysticercosis: Case reportCysticercosis is a parasitic disease caused by the larva (Cysticercus cellulosae) of pork tapeworm. Itis more common in the brain, subcutaneous tissue, muscles and eyes. We report a rare presentation ofthis disease, affecting a previously healthy 7-year-old boy...
Subject(s)
Humans , Cysticercus , Tongue Diseases , Swine , Taenia soliumABSTRACT
É apresentado caso de fibroma mole na vulva de tamanho e evolução incomuns em uma mulher na pós-menopausa.
This article describes the case of a soft fibroma of unusual size and development located in the vulva of a post-menopausal woman.